MDMA is a recreational drug that is sometimes known as molly or ecstasy. Taken for its euphoric effects, it is a popular party drug. When a person takes the drug, they experience a wide range of physical, cognitive, and emotional symptoms. In some ways, the effects of the drug can be likened to both hallucinogenic drugs as well as stimulant drugs.
Taking the substance not only causes mood changes but can also dramatically affect a person’s perception. Individuals who take MDMA often report feeling more connected to each other.
For these reasons, young people are increasingly abusing the drug. Unfortunately, abuse and addiction can be incredibly dangerous, leading to mental health problems and life-threatening overdoses.
What Does MDMA Stand For?
MDMA is an acronym for the name of a specific chemical: 3,4-methylenedioxy-methamphetamine. This chemical is a synthetic drug that causes changes in mood and perception. When a person takes the drug, it alters both their emotions and their perceptions of their environment.
MDMA has shared qualities with both stimulants and hallucinogens. It creates strong feelings of energy, pleasure, and emotional connection. The drug can also distort the perception of time, as well as sensory perception.
As a drug that helps people connect and increases energy levels, it was originally popular in the nightclub scene. In fact, the drug contributed significantly to the growth of rave culture. All-night dance parties and after-hours events quickly developed during the MDMA boom of the 90s.
Today, however, it's use has spread far beyond the rave culture. Young people are increasingly abusing MDMA alone at home, and even combining it with other substances. The consequences, unsurprisingly, are often dangerous – even fatal.
Common Street Names for MDMA
As a recreational drug, MDMA has many alternative street names. It is most commonly known as ecstasy or molly. These names can be confusing, however, since drug dealers and users often claim that they mean different things. Many people claim, for instance, that “ecstasy” refers to a variation that is combined with stimulants, such as amphetamine.
It is also widely believed that “molly” refers to a pure formulation of MDMA without any contaminants. In reality, however, almost all versions of the drug sold illicitly on the street are impure. In almost every case, drug dealers add contaminants to their product to sell more of the drug or make it seem more potent.
MDMA is commonly cut with many different contaminants, including:
- LSD
- Heroin
- Rat poison
- Caffeine
- Cocaine
- Amphetamine
Nonetheless, it is sometimes possible to use it's pure version. MDMA is increasingly being experimented with in therapeutic settings. The medical-grade versions of the drug, of course, is pure. Preliminary research has demonstrated that consumption, when administered by trained clinicians under strict supervision, has some promise for treating certain mental health disorders.
These mental illnesses include post-traumatic stress disorder (PTSD) and major depressive disorder. However, it is vital to recognize that the drug by itself does not cure these conditions. Rather, there is evidence that MDMA might, when used in conjunction with behavioral therapy, help with these conditions.
The United States Drug Enforcement Administration (DEA) classifies MDMA as a Schedule I Controlled Substance because of its high potential for abuse and addiction. Currently, there are no officially recognized benefits to using the drug, so all consumption is considered abuse.
How Does MDMA Work?
The drug works by increasing the activity of many chemicals in the brain. However, the three most important chemicals that MDMA affects are dopamine, norepinephrine, and serotonin. These neurotransmitters all play an important role in mood, energy, and perception.
- Serotonin. Serotonin is a neurotransmitter that controls appetite, mood, sleep, and other important functions. Serotonin can also activate certain hormones that control trust and sexual arousal. When large quantities of serotonin are released in the brain, people experience elevated moods, feelings of emotional closeness, and increased empathy.
- Norepinephrine. This neurotransmitter affects both blood pressure and heart rate. As a result, taking high doses of MDMA can be risky for individuals who have blood vessel problems or weak hearts.
- Dopamine. Dopamine is sometimes known as the “reward’ chemical in the brain. It plays an important role in the brain’s decision-making centers. Dopamine reinforces activities and can also reinforce addictive behaviors. It produces energy and raises activity levels.
One of the reasons why MDMA withdrawal can be so destabilizing is that these neurotransmitters are depleted after the high wears off.
What Are the Effects of MDMA?
People engage in MDMA abuse because they are seeking the strong feelings of well-being, friendliness, interconnectedness, motivation, and happiness that the drug provides. When taking it, drug abusers often believe that their 5 senses have been “improved,” due to the altered perception side effects of the drug. To sum it up, the drug basically feels quite good — at least in the short term.
Other effects of MDMA include:
- Calmness and relaxation
- Euphoria
- Lowered inhibitions
- Heightened senses
- Increased energy
- Increased sense of connection to other people
These effects are by and large experienced as subjectively positive. Unfortunately, it also causes a wide range of unpleasant and even dangerous side effects. These dangerous cognitive and physical consequences of MDMA abuse include but are not limited to:
- Nausea
- Muscle cramping
- Confusion and cognitive issues
- Sweating
- Blurred vision
- Chills
- Involuntary teeth clenching
- Mood swings
How Long Do the Effects of MDMA Last?
The MDMA “high” generally lasts no longer than 6 hours, and sometimes as short as 3 hours. When the drug is taken in the context of a nightclub or rave, it is common practice for individuals to take multiple doses. Doing so can prevent the drug from wearing off, and many people spend an entire night experiencing the “high”, which lets them continue without feeling sleep-deprived. Unfortunately, this practice dramatically increases the risks of abuse.
What Are the Psychological Effects of MDMA Abuse?
Regular abuse can lead to a wide variety of mental health disorders and cognitive difficulties. It should be noted that MDMA addiction is associated with a higher risk of developing a mental health disorder. Not only that, the relationship goes both ways: having a mental health disorder makes a person more vulnerable to addiction, as well as other substance use disorders.
According to the National Institute on Drug Abuse, roughly 50% of individuals with addictions also suffer from mental illness, and vice versa.
MDMA can provide a temporary boost to spirits. Unfortunately, this mood change is short-lived. While many individuals with depression and or anxiety turn to the drug to alleviate their pain, over time abuse is likely to exacerbate their underlying condition. This is especially true when they develop an emotional reliance on the drug.
After the effects have worn off, the body cannot produce serotonin for a short period. Serotonin, the neurotransmitter responsible for the sense of well-being, is necessary for quality mental health. By depleting it, MDMA abuse will in almost all cases harm a person’s psychological health.
Can MDMA Cause Withdrawal Symptoms?
The MDMA high is relatively short-lived. The aftereffects of taking the drug, however, can last far longer than 6 hours. In fact, the withdrawal effects can last for a week or even longer. These effects are the exact opposite of the initial positive and uplifting effects.
While it can temporarily produce feelings of euphoria, energy, and connectedness, withdrawing from the drug is more likely to make people feeling depressed, sluggish, and lonely. These symptoms can exacerbate pre-existing mental health disorders and can even make it impossible for a person to complete everyday tasks.
Most Common Side Effects of MDMA:
- Irritability
- Depression
- Sleep problems
- Aggression and impulsiveness
- Memory and attention problems
- Anxiety
- Decreased appetite
- Decreased pleasure from or interest in sex
Taking other medications alongside the drug, a practice known as polysubstance abuse, can significantly increase the severity and unpredictability of withdrawal effects. MDMA generally contains contaminants, ranging from synthetic opioids to amphetamine, which can also make withdrawal effects more dangerous. In fact, the side effects of withdrawal can even be life-threatening, especially when the drug is combined with other substances.
"},{"title":"Is MDMA Addictive?","content":"If your friend, family, or loved one is abusing MDMA, it may be difficult to tell. This is because young people generally work hard to prevent their closest loved ones from detecting their drug problems. After all, if family members discover it, it will become far more difficult to abuse it! As such, individuals who need the most help are often the last to have their problem recognized.
This is especially true with MDMA, which tends to be consumed in social settings rather than at home. This makes it far easier to conceal from family members and roommates. Nonetheless, if an individual is struggling with addiction, they will inevitably show certain signs no matter what they do to try to conceal their issue.
Learning to recognize the signs and symptoms of MDMA abuse is critical for friends and family members. Many of the most visible effects of abuse occur when a person combines the drug with other substances, such as marijuana, alcohol, prescription painkillers, and cocaine.
Individuals who use MDMA have high rates of polysubstance abuse, partly because they trust other people more and are less afraid of taking risks. As a result, individuals who abuse it are often willing to accept unidentified drugs or drinks from people they may not know.
Aside from polysubstance abuse, MDMA addiction leads to many behavioral, physical, and psychological changes.
How Does MDMA Addiction Happen?
The issue of addiction is a controversial one. Scientists do not have a definitive answer to the question of how physically addictive MDMA is. The drug does share many qualities with drugs that are physically addictive. We know it releases dopamine in the brain, which is the brain’s reward chemical that reinforces addictive behaviors. While physical dependence on the drug is poorly understood, the fact remains that in practice many people do develop addiction.
One study demonstrated that MDMA is likely inherently addictive for all mammals. When rats were placed in a cage where they had the ability to self-administer the drug, almost all rats chose to repeatedly administer it to themselves. The rats self-administered less than they did with cocaine, but the study nonetheless demonstrated that the drug may indeed be physically addictive.
One of the reasons that MDMA addiction is a bit different from other addictions is that it is difficult to abuse in the day or two after a binge. This is because taking the drug depletes the brain’s supply of serotonin. It takes the brain a few days to recover and rebuild that supply. During this time, an individual generally experiences intense withdrawal symptoms. Once they have recovered from withdrawal, they often have a strong desire to take it again.
People who develop substance use disorders with the drug tend to experience a range of negative consequences due to their abuse. They may even recognize these harms and have a strong desire to stop taking it. Once addiction has set in, however, it is very difficult to stop taking MDMA even when a person tries to do so.
In some cases, they may successfully withdraw and cease to be physically dependent. However, it is critical to recognize that substance use disorders are mental health conditions that persist long after physical dependence ends. Without a solid MDMA addiction treatment plan in place, relapse is common.
What Does MDMA Addiction Look Like?
When an individual regularly abuses MDMA they may undergo many behavior changes. Naturally, their behavior is likely to be considerably altered while they are experiencing the short-term effects of the drug. But more concerningly, their behavior is likely to be altered when they are not even high. This is especially true during the days after consuming it, when they are dealing with the ups and downs of the withdrawal.
Changes in a person’s approach to social interaction are often the most notable. MDMA, molly, and ecstasy are often used with the explicit purpose of smoothing out social interactions. They are popular drugs in the context of nightclubs, raves, and parties, due to their ability to make people feel more sociable and even more empathetic.
If your loved one seems to be suddenly more social, or if they suddenly have an entirely new peer group of “partiers,” there is a chance they have a problem.
Ironically, regular MDMA abuse also makes people less social. Withdrawal symptoms cause people to isolate themselves from friends, family members, and other loved ones. Symptoms of depression and anxiety can be exacerbated by the withdrawal. As a result, individuals recovering from it might distance themselves from hobbies and activities that they once enjoyed.
Other common behavioral changes that individuals addicted to MDMA exhibit include:
- Hostile or unpredictable mood changes
- Loss of interest in hobbies and activities
- Sleep disturbances
- Uncooperative attitude
- Worsened performance at school or work
- Social isolation
Individuals abusing MDMA sometimes also become more sexually active. The reasons are partly contextual: the drug is especially common at nightclubs, raves, and other events where heightened sexual activity is the norm. It can foster feelings of connection with other people and cause people to experience increased trust. Risk-taking behavior is also common.
Many users combine MDMA with other drugs, including sildenafil (Viagra). This combination increases the possible negative harms. Consequences of increased sexual activity from drug abuse include unwanted pregnancy, an increased risk of assault, and a higher likelihood of contracting a sexually transmitted infection (STI).
Long-Term Dangers of MDMA Addiction
Abusing MDMA can lead to many problems in a person’s life, and these tend to get worse over time. Health and behavioral problems may already be problematic in the short term, but over the long term, severe and even life-threatening issues can occur. Once a person has developed a physical or psychological dependence on the drug, then they will feel that they require the drug to feel happy or to function.
Over time, they may come to prioritize MDMA abuse over all other activities, relationships, and goals. As their lives narrow and the drug becomes the focal point, addicts may find themselves having less and less to live for aside from their addiction.
Other long-term consequences of MDMA abuse include:
- Memory loss
- Anxiety, depression, and other mental health disorders
- Impaired functioning in parts of the brain that control sleep, learning, and emotion
- Long-term brain damage
- Damaged nerve branches and nerve endings
- Kidney failure
- Hemorrhaging
- Convulsions
- Psychosis
- Cardiovascular collapse
- Death
MDMA abuse does not directly lead to an overdose. However, it's effects can often indirectly lead to potentially life-threatening health issues. In this sense, overdose is a real threat. In fact, the Substance Abuse and Mental Health Services Administration (SAMHSA) estimates that every year 10,000 young people under the age of 21 have to go to the emergency room due to MDMA overdoses.
The greatest dangers of MDMA abuse occur when the body overheats. The drug has a significant impact on the body systems that control and regulate body temperature. When it is taken in a calm environment by a relatively stationary person, these changes in body temperature are not significant.
However, MDMA is frequently taken in hot and crowded environments, such as nightclubs and raves. Dancing and other intense, physically taxing activities are the norms in these places. The drug increases energy levels and often results in users straining their bodies more than they otherwise would.
As a result, MDMA abuse can result in hyperthermia. Hyperthermia is the clinical term for a dangerous spike in body temperature. Hyperthermia can rapidly cause major life-sustaining body functions to shut down. During an overdose, hyperthermia can have the following consequences:
- Dehydration
- Brains swelling
- Muscle breakdown
- Kidney failure
- Imbalanced electrolytes
- Liver failure
- Heart failure
- Death
It is also possible to overdose on MDMA when the drug is laced with other substances. While directly overdosing on the drug is difficult, the fact remains that the drug is seldom pure. It is often contaminated with ketamine, methamphetamine, cocaine, bath salts, even powerful synthetic opioids like fentanyl. These drugs, especially when taken unwittingly, can easily lead to life-threatening overdoses.
"},{"title":"MDMA Addiction Treatment Center in Los Angeles","content":"There is no specific medical treatment designed for MDMA addiction. Currently, there are no medications that reduce cravings for MDMA. While there may not be an specific medical MDMA addiction treatment, however, a combination of treatments can help with addiction more generally. In the case of addiction, research and rehab statistics have shown behavioral therapy to be especially helpful.
Outpatient treatment programs help individuals who are suffering from MDMA abuse. At an outpatient drug rehab in LA, individuals can attend treatment sessions as infrequently as once a week or as frequently as every day, depending on their needs and flexibility.
At an outpatient treatment center such as Nuview Treatment Center, clients take part in a wide range of behavioral therapies, including dialectical behavioral therapy (DBT), cognitive-behavioral therapy (CBT), and acceptance and commitment therapy (ACT). They also learn important life skills, coping tools, develop strong social support systems, and work to build newfound lives for themselves in sobriety.
"},{"title":"Frequently Asked Questions","content":"What Does MDMA Stand For? MDMA is an acronym for the name of a specific chemical: 3,4-methylenedioxy-methamphetamine. This chemical is a synthetic drug that causes changes in mood and perception. When a person takes the drug, it alters both their emotions and their perceptions of their environment. What are the Effects of MDMA?Taken for its euphoric effects, ecstasy is a popular party drug. When a person takes the drug, they experience a wide range of physical, cognitive, and emotional symptoms. In some ways, the effects of the drug can be likened to both hallucinogenic drugs as well as stimulant drugs.
Taking the substance not only causes mood changes but can also dramatically affect a person’s perception. Individuals who take MDMA often report feeling more connected to each other.
For these reasons, young people are increasingly abusing the drug. Unfortunately, abuse and addiction can be incredibly dangerous, leading to mental health problems and life-threatening overdoses.
People engage in MDMA abuse because they are seeking the strong feelings of well-being, friendliness, interconnectedness, motivation, and happiness that the drug provides. When taking it, drug abusers often believe that their 5 senses have been “improved,” due to the way the drug’s side effects change perception. To sum it up, the drug basically feels quite good — at least in the short term.
Other effects of MDMA include:
- Calmness and relaxation
- Euphoria
- Lowered inhibitions
- Heightened senses
- Increased energy
- Increased sense of connection to other people
While most of the immediate effects of molly are by and large experienced as subjectively positive, most users experience negative side effects as well. MDMA consumption can lead to a wide range of unpleasant and even dangerous side effects. These dangerous cognitive and physical consequences of MDMA abuse include but are not limited to:
- Nausea
- Muscle cramping
- Confusion and cognitive issues
- Sweating
- Blurred vision
- Chills
- Involuntary teeth clenching
- Mood swings
The MDMA high is relatively short-lived. The aftereffects of taking the drug, however, can last far longer than 6 hours. In fact, the withdrawal effects can last for a week or even longer. These effects are the exact opposite of the initial positive and uplifting effects.
While it can temporarily produce feelings of euphoria, energy, and connectedness, withdrawing from the drug is more likely to make people feeling depressed, sluggish, and lonely. These symptoms can exacerbate pre-existing mental health disorders and can even make it impossible for a person to complete everyday tasks.
Most Common Side Effects of MDMA Withdrawal:
- Irritability
- Depression
- Sleep problems
- Aggression and impulsiveness
- Memory and attention problems
- Anxiety
- Decreased appetite
- Decreased pleasure from or interest in sex
Taking other medications alongside the drug, a practice known as polysubstance abuse, can significantly increase the severity and unpredictability of withdrawal effects. MDMA generally contains contaminants, ranging from synthetic opioids to amphetamine, which can also make withdrawal effects more dangerous. In fact, the side effects of withdrawal can even be life-threatening, especially when the drug is combined with other substances.
How Does MDMA Affect the Brain?The drug works by increasing the activity of many chemicals in the brain. However, the three most important chemicals that MDMA affects are dopamine, norepinephrine, and serotonin. These neurotransmitters all play an important role in mood, energy, and perception.
- Serotonin. Serotonin is a neurotransmitter that controls appetite, mood, sleep, and other important functions. Serotonin can also activate certain hormones that control trust and sexual arousal. When large quantities of serotonin are released in the brain, people experience elevated moods, feelings of emotional closeness, and increased empathy.
- Norepinephrine. This neurotransmitter affects both blood pressure and heart rate. As a result, taking high doses of MDMA can be risky for individuals who have blood vessel problems or weak hearts.
- Dopamine. Dopamine is sometimes known as the “reward’ chemical in the brain. It plays an important role in the brain’s decision-making centers. Dopamine reinforces activities and can also reinforce addictive behaviors. It produces energy and raises activity levels.
Dr. Ryan Peterson, MD, specializes in Addiction Medicine and Pain Management in Los Angeles, with advanced training from The George Washington University, St. Vincent's Hospital, Weill Medical College of Cornell University, and UCLA Hospital. Currently accepting new patients.
Seeking Assistance but Finding It Difficult to Have a Conversation Just Yet?
Feel at ease and opt for our text support, which offers:
- Valuable resources on substance use and recovery
- Insight into our nurturing treatment approach
Remember, we are available 24/7 to address any concerns or inquiries.
Questions About Treatment Options For Substance Use?
Our admission specialists are available 24/7 to listen to your story and get you started with next steps.
Check to See if Your Insurance is in-network at Our Rehab Facility.
Verify Your Insurance
Everyone is Welcome Here and
We All have Your Back
We are here to help guide you on your path to recovery. Speak confidentially with one of our substance use specialists about finding a program that is right for you.
Written By
Dr Ryan Peterson