Disclaimer: This article is for educational purposes only and does not replace expert medical or mental health advice. Lexapro prescription and dosage require a comprehensive evaluation by a qualified clinician. So, always refer to a board-certified physician or psychiatric practitioner for specific direction or treatment.
Lexapro (generic name: escitalopram) is a medication used to treat anxiety and major depressive disorders. How long Lexapro stays in your system can depend on the dosage and frequency of use, among other things. On average, it may stay in your system 6 - 7 days after the last dose. However, depending on the type of drug test used, it can be detected for even longer.
What Is Lexapro Half-Life?
The half-life of Lexapro (escitalopram) is estimated to be 27 to 32 hours. It refers to the time taken for the medication in your system to be reduced by half, then another half of the remaining half, and so on. It typically takes 4 to 5 half-life cycles before the medication is entirely cleared from your system.
As Lexapro has a longer half-life than the average medication, it takes nearly 6 to 7 days before the medication leaves your system.
How Long Does Lexapro Stay In Your System?
Lexapro stays in your system for 6 or 7 days after the last dose. However, depending on the drug testing method used - it can be detected for shorter or longer periods of time.
How Long Does Lexapro Stay In Your Urine?
Lexapro can be detected in your urine for 3 to 6 days after the last dose. As urine tests are inexpensive and easy to administer, they are the most commonly used drug testing methods.
How Long Does Lexapro Stay In Your Saliva?
Lexapro can be detected in your saliva for 1 to 4 days after the last dose. Saliva tests are the least invasive and easier to administer as well.
How Long Does Lexapro Stay In Your Blood?
Lexapro can be detected in your blood for 6 to 7 days after the last dose. As blood tests are more invasive than the other tests, they are not as commonly used except in clinical settings for accurate results.
How Long Does Lexapro Stay In Your Hair?
Lexapro can be detected in your hair for up to 90 days. As hair tests are expensive and time-consuming, they are not commonly used except to establish a history of Lexapro use.
| Test Type | Detection Window |
| Urine | 3 - 6 days |
| Saliva | 1 - 4 days |
| Blood | 6 - 7 days |
| Hair | Up to 90 days |
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When It Is Worth Talking To Reach Out
If you are unsure how Lexapro is affecting you or whether your experience is typical, it is worth getting clarity. Speak to a licensed and experienced mental health specialist and understand what this looks like for you.
What Factors Impact How Long Lexapro Stays In the System?
Lexapro can stay in the system up to 6 to 7 days; however, some factors can impact this timeline:
- Dosage and Frequency: Higher doses and frequency of use can lead to SLOW down the elimination time.
- Metabolism: Metabolism is responsible for breaking down Lexapro in your system. Faster or slower metabolism rates can impact how long Lexapro stays in the body.
- Age: As age can slow down the metabolism rate, it can slow down the elimination time.
- Liver and Kidney Functioning: The liver and kidneys play a central role in metabolism and excretion, respectively. Therefore, pre-existing liver and kidney conditions can impact how long the medication can stay in the system.
- Body Weight: Decreasing body weight can slow down the elimination rate.
Can You Get Lexapro Out of the System at a Faster Rate?
When it comes to getting Lexapro out of the system, the body must take action. However, there are some steps you can take to strengthen your body's functioning.
Eating nutritious meals, keeping your body hydrated, getting consistent rest, and regular exercise can enable your body’s overall health and functioning, and can facilitate getting Lexapro out of your system in a healthy way.
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Is Lexapro Addictive?
Lexapro or escitalopram is a selective serotonin reuptake inhibitor (SSRI); it is used to treat anxiety and depressive symptoms, but is not known to be clinically addictive. However, prolonged use can lead to dependence. Stopping Lexapro use abruptly can lead to withdrawal symptoms, such as:
- Mood shifts
- Irritability and agitation
- Vomiting
- Dizziness
- Burning, tingling, or numbing sensations
- Headaches
- Sleeplessness
- Sweating
- Shaking
- Tiredness.
This is why Lexapro must only be taken under the close supervision of a board-certified physician or psychiatric practitioner. If you want to make any adjustments or stop the medications, refer to your doctor first. They will recommend a slow taper to manage withdrawal symptoms safely.
A Word From NuView
If you are struggling with anxiety or depressive symptoms, reach out to the NuView Treatment Center today. Our licensed and experienced clinical team integrates safe medication management with behavioral therapy for an empowering healing journey.
If you are interested in exploring structured care options without stepping away from your life, we also offer:
- Partial Hospitalization Programs (PHP): PHPs offer a higher level of structured care for anxiety and major depressive disorder. It runs for 6 hours per day for 5 days per week.
- Intensive Outpatient Programs (IOP): IOPs offer both structure and flexibility - they run for 9-15 hours per week, with personalized scheduling options that can be built around your daily life and routines.
You Do Not Have to Figure This Out On Your Own
If something about your experience with Lexapro or anxiety/depression feels unclear, you do not have to navigate this on your own. Reach out to us to explore your next steps in a safe and confidential setting toward a healthier tomorrow.
Frequently Asked Questions About How Long Does Lexapro Stay In the System
How does Lexapro work?
Lexapro is an SSRI, so it works by increasing the serotonin activity in the brain, the chemical messenger that regulates mood. In doing so, it offers relief from anxiety and depressive symptoms.
How long does it take for Lexapro to work?
While it takes a few hours for Lexapro to increase the serotonin activity in your brain, it may take at least 2 months to notice a difference in anxiety or depressive symptoms.
When does Lexapro reach peak level?
Lexapro reaches peak level 5 hours after consumption; this is when it is at its most effective.
Is Lexapro effective on its own for anxiety or depression?
Lexapro is best combined with behavioral therapies and social support for an empowering healing journey.
How can Lexapro withdrawal symptoms be treated?
Typically, your doctor will recommend a slow taper so that you can safely withdraw from Lexapro use. This is why any changes in the medication or stopping the medication must only be done under the close supervision of your doctor.
- What Is Lexapro Half-Life?
- How Long Does Lexapro Stay In Your System?
- What Factors Impact How Long Lexapro Stays In the System?
- Can You Get Lexapro Out of the System at a Faster Rate?
- Is Lexapro Addictive?
- A Word From NuView
- Frequently Asked Questions About How Long Does Lexapro Stay In the System
- What Is Lexapro Half-Life?
- How Long Does Lexapro Stay In Your System?
- What Factors Impact How Long Lexapro Stays In the System?
- Can You Get Lexapro Out of the System at a Faster Rate?
- Is Lexapro Addictive?
- A Word From NuView
- Frequently Asked Questions About How Long Does Lexapro Stay In the System
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Written By
Dr. Ryan Peterson